Diogo Jota scored a hat-trick for Wolves as they thrashed Espanyol in their Europa League last-32 clash.
Nuno Espirito Santo’s side have a four-goal lead to protect on their trip to Spain for the second leg after the thrilling 4-0 win at Molineux.
The home side took just 15 minutes to claim the lead as Jota scored his first from close range.
Ruben Neves extended Wolves’ lead with a spectacular volley from outside the area.
Espanyol could only clear a Traore cross as far as Neves who chested the ball down before volleying in from 25 yards after 52 minutes.
Jota got his second goal of the game to put Wolves 3-0 ahead when he fired into the top corner after 67 minutes and completed his hat-trick in the final few minutes.
Man United had to settle for a 1-1 draw with Club Brugge but take an important away goal back to Old Trafford.
Brugge caught the United defence napping with a long ball over the top which saw Emmanuel Dennis lob Sergio Romero after 15 minutes.
Mignolet hit a long goal kick which caught out the United backline and Dennis was first to the ball before lobbing the advancing goalkeeper.
United were level 10 minutes before the break when Anthony Martial stole the ball at a home throw.
The forward then beat the last defender before slotting home to draw United level at 1-1.
Former Liverpool keeper Mignolet prevented Martial adding to United’s tally as he finger-tipped a low shot on to the post just before the break as the first half ended 1-1.
Odion Ighalo was introduced midway through the second half for his Europa League debut for United to try and provide them with a spark.
Bruges squandered a golden opportunity in the 77th minute when Kossounou scuffed his shot on goal wide of the post.
Bruno Fernandes’ introduction immediately improved the United side and created a barrage of chances in the final 10 minutes but failed to find the winner.
Arsenal scored late on to take a 1-0 win against Olympiakos back to the Emirates for the second leg.
Alexandre Lacazette returned to Mikel Arteta’s starting line-up but a toothless Gunners attacked created little in the way of chances for most of the match.
David Luiz had a couple of long distance efforts in the second half that failed to trouble to Olympiamkos goalkeeper.
The home side had chances of their own by Bernd Leno was more than up to the task.
Lacazette netted the winner nine minutes from the end when he was given an easy chance by Bukayo Saka.
Celtic also took home a vital away goal as they drew 1-1 at FC Copenhagen.
Neil Lennon’s side went ahead with 14 minutes on the clock through Odsonne Edouard, the striker dinking the ball over the keeper to open the scoring.
Copenhagen were back in the tie seven minutes into the second half as Dame N’Doye stuck to make it 1-1.
The hosts then had a penalty late on to go ahead but Fraser Forster saved to earn his side a draw.
Rangers came back from 2-0 down to win 3-2 in their thrilling match at home to Sporting Braga.
Steven Gerrard’s side suffered an early setback as Braga went in front with just 11 minutes gone.
Fransergio opened the scoring for the visitors with a shot from long range.
Braga increased their lead against Rangers just before the hour when Abel Ruiz fired into the corner of the goal after cutting through the home defence.
Ianis Hagi gave Rangers hope as he made it 2-1 with 23 minutes remaining.
Rangers were level with 15 minutes to go as Joe Aribo cut in from the left and evaded four defenders before curling a low shot into the goal.
The comeback was then completed eight minutes from time when Hagi netted his second to make it a good night for the British sides.
Full results from Europa League early kick-offs:
CFR Cluj 1-1 Sevilla
Bruges 1-1 Manchester United
Eintracht Frankfurt 4-1 Red Bull Salzburg
Copenhagen 1-1 Celtic
Getafe 2-0 Ajax
Ludogorets 0-2 Inter Milan
Shakhtar Donetsk 2-1 Benfica
Sporting Lisbon 3-1 Istanbul Basaksehir
Europa League late kick-offs:
Apoel Nicosia 0-3 Basel
AZ Alkmaar 1-1 LASK
Bayer Leverkusen 2-1 Porto
Olympiakos 0-1 Arsenal
Rangers 3-2 Sporting Braga
Roma 1-0 Gent
Wolfsburg 2-1 Malmo
Wolves 4-0 Espanyol