Goals from Nathan Ake, Harry Wilson and Callum Wilson saw Bournemouth claim a 3-1 win at south coast rivals Southampton – their first ever triumph away against Saints in their 129-year history.
James Ward-Prowse’s second-half penalty did make it an exciting contest but England international Wilson’s stoppage-time strike sealed the three points and third place in the Premier League for Eddie Hearn’s men.
Before the match, Howe called on his players to break their duck of not being able to beat Southampton on their home turf.
These words had the desired effect as they started much better and took the lead on ten minutes through Ake’s towering header.
The Dutchman shrugged off pressure from Oriel Romeu and Kevin Danso before nodding the Diego Rico’s corner from the right past Angus Gunn.
Josh King thought he’d doubled the Cherries’ lead but his composed finish was eventually ruled out following a VAR check – replays showing the forward was marginally offside.
But Bournemouth did have their second ten minutes before the break through Wilson’s finish.
Philip Billing started the move down the left and his cut-back was met by Wilson, who nipped in ahead of Jannik Vesetergaard before squeezing the ball into the corner of the net.
This prompted the hosts to have their best chance of the first-half but Aaron Ramsdale saved Pierre-Emile Hojbjerg’s shot from point-blank range.
Ralph Hasenhuttl’s side were much better after the break and they were given a route back into the game when Che Adams was felled by Steve Cook. Ward-Prowse made no mistake from the resulting spot-kick.
Bournemouth then had a penalty appeal of their own, however, referee Chris Kavanagh waved them away after King went down from a challenge on Cedric.
The incident was also looked at by VAR and the spot-kick was not awarded.
Saints huffed and puffed and would have been level but Nathan Redmond’s goalbound shot was well blocked by Jack Stacey.
Ramsdale then made a smart stop to deny Ward-Prowse’s deflected effort while Sofiane Boufal also went close.
There would be one more goal but it went to Bournemouth as some confusion between Gunn and Jan Bednarek saw the ball break to striker Wilson, who passed the ball into an empty net to send the travelling Cherries fans wild.